Syphilis Testing

A syphilis infection poses serious health risks. In recent years, the rates of syphilis infection have shown a marked increase especially in MSM (men who have sex with other men) and in infants born to mothers who are infected with syphilis. Having a syphilis infection also increases your risk of HIV infection. Fortunately, syphilis is a curable STD, but early detection is vital to the successful treatment of a syphilis infection.

The Rapid Plasma Reagin (RPR) Blood Test, conducted by an STDAware lab, uses the FDA Approved testing methodology called flocculation to screen for syphilis. The RPR blood test will look for antibodies to the syphilis virus in the blood. The lab will require a small sample of your blood to perform this test. You will not need to remove your clothing or wear a gown. You may be asked to roll up your shirt-sleeve.

Quick View Of Syphilis Testing


You do NOT need to fast before the syphilis RPR blood test

Sample Needed

This test requires a blood sample only

Test Time

5-10 Minutes


Back in 1-2 days


One of our doctors will contact you if you test positive for having syphilis

What Type Of Sample Does This Test Require?

The Rapid Plasma Reagin (RNR) Blood Test is a blood test only. When you visit an STDAware lab, a small amount of blood will be drawn. This test does not involve any cups, invasive swabbing, or uncomfortable scrapings.

How Long Does It Take To Get Tested?

Most STDAware patients are typically in and out of the laboratory-testing center within 10 – 15 minutes.

Do I Need To Fast Before Getting Tested For Syphilis?

No. You do not need to abstain from eating and drinking before this Syphilis blood test.

How Long Does It Take To Get My Results?

Test results are typically available with in 1-2 days. To learn more about how STDAware makes getting tested quick and convenient for you, click here.

Should I Get Tested For Syphilis?

The Rapid Plasma Reagin (RPR) Blood Test for syphilis will look for antibodies to the syphilis virus in the blood sample. The RPR test can be done 1-3 months after suspected exposure and yield accurate results, but it is advised to follow up with a confirmation test between 3-4 months after initial suspected exposure to confirm a negative status.

Failure to identify and treat a syphilis infection can result in severe and irreparable damage to the internal organs, brain function, and could even lead to death.

Any sexually active individual is at risk of a syphilis infection. Individuals who are at increased high risk of contracting syphilis are those who engage in unprotected vaginal or anal sex, have had multiple sex partners, have another type of STD infection, or have ever shared needles with anybody. MSM individuals have been reported to have an increased instance of syphilis infection and should consider regular testing as part of their overall healthcare routine.

Routine and proactive syphilis testing should be part of an overall healthy lifestyle.

It is possible for you to be infected with syphilis and not exhibit any symptoms until critical damage has been done to the body.


In the event that your test results come back positive, one of the STDAware doctors will attempt to reach you by phone, within two days, after your test before releasing results via email. The doctor will try to make contact three times, over the span of one week, before sending your test results through to the secure patient portal.

If you are worried that you may have missed the doctor’s phone call, please contact us toll free: 1-855-588-6958 or email:

What will the results show?

The test results for syphilis will reflect one of the two types of outcomes: "Non-reactive" or "Reactive."

  • Non-reactive Test Result: means that you do not have a syphilis infection but a follow-up test to confirm is recommended
  • Reactive Test Result: means your test revealed antibodies to the syphilis virus in your blood sample. Further testing may be required. An STDAware doctor will reach out to you to go over your test results and treatment options

Can Syphilis Be Cured?

Syphilis can be cured with a prescription series of antibiotics. Treatment for syphilis does not create immunity to the disease, and a person can be infected again if they do not exercise safe sex practices. Additionally, syphilis treatment cannot undo any damage caused by the virus prior to treatment.

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Get Tested for Syphilis

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Visit your lab of choice the same day you order your test. No appointment necessary! Get in and out within 10 – 15 minutes.

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4. View your Results

View your results in 2 days or less in our secure patient portal.

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What If I Test Positive for Syphilis?

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If you test positive for having Syphilis one of our board certified physicians may attempt to reach out to you on the phone for a free post-test consultation. If you are unavailable by phone, we will reach out to you at the email address provided when you purchase your test. On your consultation call, our doctor will explain your results to you and what options you have for treatment. Syphilis can be cured with antibiotics. Early detection is critical in treating a syphilis infection before the disease causes permanent and serious damage to the heart and brain. Don't Wait! Get Tested.

View Sample Results

Your testing information and results are private, safe, and secure. To learn more about how STDAware makes your privacy a priority, click here.

STDAware Is A Trusted Syphilis Testing Provider

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  • Quick, affordable and discrete! I will definitely recommend this to others.

  • Very satisfied with my experience, everything was fast and efficient, just what I needed!

  • Well....I made a little mistake :| Luckily this site helped me know sooner than later ugggghhhh....I can honestly say if you are in this bad situation that these guys can help, and not judge...they were more than cordial heh.

  • Checkout process was surprisingly easy and straightforward. I wasn't sure if this was going to work out, but there were a few test centers like 15 minutes from me, so that was pretty good. Update: When I got to the test center, I only had to wait a few minutes, and they made everything really easy. Thanks.

-STDAware Patient

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